Syria 2500 BC
Agriculture has probably been practiced for longer here than anywhere else in the world. By this time, important trade routes run through Syria and Canaan between Mesopotamia1)http://www.timemaps.com/history/iraq-2500bc to the east and Egypt2)http://www.timemaps.com/history/ancient-egypt-2500bc to the south, both by land and sea. These trade routes have brought the influences of Mesopotamian and Egyptian civilizations into the region, and small city-states now scatter the region. The city of Byblos, on the Syrian coast, is an important port, is home of a thriving shipping trade with Egypt and other Mediterranean regions.
Original Source: timemaps.com